Instructions: Click on the "Start" button to view a slide show of the gallery (5 seconds per image) Click on the arrow buttons to browse the gallery Select an item from the drop-down menu to view an image Windows Internet Explorer users: Press F11 to view this page in full screen (F11 to return)

*~*~*~* The Biology of Trichinella spiralis *~*~*~* Life Cycle of Trichinella spiralis Geographic Distribution of Trichinella Species       *~*~*~* Morphology of the Nurse Cell *~*~*~* Trichinella spiralis -- Breaking and Entering Worm Entering Muscle Cell Newborn Larva Entering a Muscle Cell Stylet Larva 10 minutes after Penetrating Muscle Electron micrograph of the larva 1 hour after entering the muscle cell       *~*~*~* Nurse Cell Formation *~*~*~* Loss of Muscle Specific Proteins (actin, myosin, creatine kinase) Mitochondrial Damage Secretion of Tyvelosylated Proteins DNA Sythesis and Nuclear Enlargement Collagen Type IV Synthesis Collagen Type VI Synthesis Induction of VEGF       *~*~*~* De-differentiation *~*~*~* Normal Unifected Muscle EM of Infected Muscle (3 Days Post-infection) EM of Infected Muscle (5 Days Post-infection) EM of Infected Muscle (6 Days Post-infection) EM of Infected Muscle (8 Days Post-infection ) Mature Nurse Cell Cytoplasm Granule Containing Cells of the Newborn Larva EM of the Stichocyte of Mature Muscle Larva       *~*~*~* Re-differentiation *~*~*~* Molecular Structure of Tyvelose Epicuticle of T. spiralis contains tyvelosylated proteins       *~*~*~* The End *~*~*~*